A biological phenomenon known as RNA interference occurs when target mRNA molecules are neutralized and RNA molecules are seen to impede the translation or production of genes. Moreover, RNA interference (RNAi) is a group of tiny RNA-directed processes that suppress genetic expression in a sequentially specified manner. Many researchers were instantly interested in the concept that RNA interference (RNAi) could introduce a new class of treatment. From the lab to the bedside, the field of applied RNA interference therapy has seen a rapid expansion of experimentation. Drug development frequently employs the RNAi method, and phase I and II clinical trials are now under progress. Moreover, RNA interference therapy allows for the silencing of particular, highly efficient genes. Targeting rib nucleotide seeds (RNA) is thought to be an effective use of RNAi therapeutics since they offer the chance to change gene expression. Oncology, cardiovascular, respiratory, renal, neurological, genetic, and viral diseases are among the many conditions for which it is utilized extensively. The Global RNAi Therapeutics Market is expected to expand at a CAGR of 8.4% between 2023 and 2030.
RNAi Therapeutics Market Major Driving Forces
Increasing Numbers of Chronic Illness Cases: The market's growth will be accelerated by the increasing prevalence of chronic illnesses such as cancer, heart problems, and other ailments. Additional factors including more RNAi therapeutic approvals, improvements in the healthcare industry, increased R&D spending, and increased pharmaceutical company collaborations will drive the RNAi therapeutics market even further.
Growing Aging Population: The aging population is another driver propelling the global market for RNAi therapeutics. Older adults are prone to suffer from serious illnesses such as cancer. These individuals therefore need the best care and prompt treatment for their conditions, which increases the market potential for RNAi therapies globally.
Technological Developments: The global market for RNAi therapies is poised to expand as a result of recent technology advancements. Thus, the application of cutting-edge technology supports the global market's development of novel RNAi treatments.
Growing Prevalence of Genetic Disorders: RNAi therapies research and development have been fueled by the rising incidence of genetic disorders and diseases having a genetic component. RNA interference (RNAi) has the ability to target and silence particular genes linked to various illnesses.
RNAi Therapeutics Market Key Opportunities
Targeting Undruggable Genes: RNAi technology offers a unique advantage in targeting genes that were previously considered undruggable by traditional pharmaceutical approaches. This expands the range of potential therapeutic targets, opening up new avenues for drug development.
Growing Number of Cancer Cases: The fast-paced lifestyle and contaminated surroundings have led to a definite increase in cancer incidence worldwide, according to statistics data. The market for RNAi therapeutics is expected to expand because more people are aware of the most recent treatments available for cancer.
Personalization: More and more patients are looking for individualized care and medicines. Targeting particular genomic sequences, RNAi therapies provide individualized treatment plans that take into account each patient's unique genetic composition.
RNAi Therapeutics Market Key Trends
· The goal of ongoing research and development has been to enhance RNAi therapeutic delivery.
· To increase the potential market reach, researchers and pharmaceutical companies are investigating uses in the areas of infectious diseases, neurological disorders, cardiovascular diseases, and metabolic problems.
· There are more and more candidates moving through the preclinical and clinical stages of the RNAi therapies trial pipeline.
· Academic institutions, biotech companies, and pharmaceutical companies continue to collaborate and form partnerships.
· The development of RNA interference (RNAi) medicines to treat uncommon genetic illnesses is becoming more and more important.
· Researchers are looking at using RNA interference (RNAi) therapies for immune modulation in addition to direct gene silencing.
Market Competition Landscape
The presence of both domestic and foreign competitors defines the competitive landscape of the RNAi therapies market. Due to mergers and acquisitions, wherein larger corporations have bought smaller enterprises in order to enhance their market position and develop their skills, the RNAi therapeutics sector has concentrated. Notable businesses with a broad range of goods and services and a global presence have arisen as a result of this trend. Businesses in the RNAi therapeutics market are embracing innovative technologies fast in order to increase project safety and efficiency. Companies with a broad geographic reach can access a wider range of markets and opportunities more effectively. By leveraging their local or global presence, they can expand their project portfolio and gain a larger market share. Key players in the global RNAi therapeutics market implement various organic and inorganic strategies to strengthen and improve their market positioning. Prominent players in the market include:
· Quark Software Inc.
· F. Hoffmann-La Roche Ltd.
· Rexahn Pharmaceuticals, Inc.
· Silence Therapeutics
· Arbutus Biopharma
· Benitec Biopharma
· GSK plc
· OLIX PHARMACEUTICALS, INC.
· Sanofi
· Alnylam Pharmaceuticals, Inc.
· Moderna Inc.
· Ionis Pharmaceuticals
Report Attribute/Metric |
Details |
Base Year |
2022 |
Forecast Period |
2023 – 2030 |
Historical Data |
2018 to 2022 |
Forecast Unit |
Value (US$ Mn) |
Key Report Deliverable |
Revenue Forecast, Growth Trends, Market Dynamics, Segmental Overview, Regional and Country-wise Analysis, Competition Landscape |
Segments Covered |
· By Molecule Type (Small Interfering RNAS, Microrna) · By Application (Genetic Disorder, Oncology, Neurodegenerative Disorder, Cardiovascular Disorder, Respiratory Disorder, Infectious Disease, Renal Disease, Other) · By Route of Administration (Intradermal Injections, Pulmonary Delivery, Intravenous Injections, Intraperitoneal Injections, Others) · By End- User (Diagnostic Laboratories, Research and Academic Laboratories, Hospitals) |
Geographies Covered |
North America: U.S., Canada and Mexico Europe: Germany, France, U.K., Italy, Spain, and Rest of Europe Asia Pacific: China, India, Japan, South Korea, Southeast Asia, and Rest of Asia Pacific South America: Brazil, Argentina, and Rest of Latin America Middle East & Africa: GCC Countries, South Africa, and Rest of Middle East & Africa |
Key Players Analyzed |
Quark Software Inc., F. Hoffmann-La Roche Ltd., Rexahn Pharmaceuticals, Inc., Silence Therapeutics, Arbutus Biopharma, Benitec Biopharma, GSK plc, OLIX PHARMACEUTICALS, INC., Sanofi, Alnylam Pharmaceuticals, Inc., Moderna Inc., Ionis Pharmaceuticals |
Customization & Pricing |
Available on Request (10% Customization is Free) |